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Phenotypes Associated with This Genotype
Genotype
MGI:3794045
Allelic
Composition		 Mus81tm1Esse/Mus81+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mus81tm1Esse mutation (0 available); any Mus81 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal aorta wall morphology ( J:133703 )
• subtle changes including reduction in translucence of the aortic wall
• accumulation of excess amorphous matrix material between elastic fibers; however, no defect in fiber integrity is seen
abnormal subclavian artery morphology ( J:133703 )
• abnormal ballooning of the proximal right subclavian artery

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory