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Phenotypes Associated with This Genotype
Genotype
MGI:3789903
Allelic
Composition		 Cckartm1Kpn/Cckartm1Kpn
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cckartm1Kpn mutation (2 available); any Cckar mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuronal migration ( J:96891 )
• the increased number of GnRH-1 neurons found in the forebrain of E14.5 embryos is indicative of an accelerated neuronal migration from the nose towards the brain during development
abnormal forebrain morphology ( J:96891 )
• the forebrain of E14.5 embryos contains 16-20% more gonadotropin-releasing hormone-1 neuroendocrine (GnRH-1) neurons than in wild-type embryos

cellular
abnormal neuronal migration ( J:96891 )
• the increased number of GnRH-1 neurons found in the forebrain of E14.5 embryos is indicative of an accelerated neuronal migration from the nose towards the brain during development

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory