Phenotypes Associated with This Genotype

Genotype
MGI:3789308

• Allelic Composition: En2^tm2Alj/En2^tm2Alj
• Genetic Background: involves: 129S2/SvPas * Swiss Webster

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

decreased inferior colliculus size ( J:134516 )

• reduced in size at E18.5

• in adults, IC is truncated

abnormal cerebellum morphology ( J:134516 )

• size is slightly reduced at E11.5

abnormal cerebellum vermis morphology ( J:134516 )

• in E18.5 mutants, there is a general delay in fissure formation in vermis

• in adults, vermis is reduced in size

abnormal cerebellum posterior vermis morphology ( J:134516 )

• folium VIII position is shifted posteriorly and is associated with folium IX instead of with VI/VII

small cerebellum ( J:134516 )

• overall size reduced by one-third