Phenotypes for En1 En2 MGI:3789302 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	En1^tm2Alj/En1^tm2Alj En2^tm2Alj/En2⁺
Genetic Background	involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1^tm2Alj mutation (1 available); any En1 mutation (34 available)
En2^tm2Alj mutation (0 available); any En2 mutation (107 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality, complete penetrance ( J:134516 )

• no mutants are detected after birth

nervous system

absent inferior colliculus ( J:134516 )

• absent at E18.5

absent superior colliculus ( J:134516 )

• absent at E18.5

absent colliculi ( J:134516 )

absent tectum ( J:134516 )

absent cerebellum ( J:134516 )

• at E18.5, no cerebellum is observed

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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