Phenotypes for En1 MGI:3789299 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	En1^tm2(cre)Wrst/En1^tm8.1Alj
Genetic Background	involves: 129/Sv * Black Swiss * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1^tm2(cre)Wrst mutation (1 available); any En1 mutation (32 available)
En1^tm8.1Alj mutation (1 available); any En1 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal inferior colliculus morphology ( J:134516 )

abnormal cerebellum anterior vermis morphology ( J:134516 )

• in most adult mice, mild foliation defect is observed

• fissure between anterior-most folia I/II and III either fails to form or is shallower than normal in most animals

• at E18.5, vermis may be slightly delayed in forming folia

decreased anterior vermis size ( J:134516 )

• overall size in some mutants is slightly reduced relative to wild-type at E18.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23