Phenotypes Associated with This Genotype

Genotype
MGI:3785251

• Allelic Composition: Ighmbp2^nmd-2J/Ighmbp2^nmd-2J; Tg(Eno2-Ighmbp2)90Cx/?
• Genetic Background: involves: C57BL/6J * C57BLKS/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:90418 )

• phenotype is stated to be identical to that observed when Tg(Eno2-Ighmbp2)17Cx mice are used in this cross (GA Cox, personal communication)

growth/size/body

weight loss ( J:90418 )

cardiovascular system

abnormal cardiovascular system physiology ( J:90418 )

dilated cardiomyopathy ( J:90418 )

abnormal impulse conducting system conduction ( J:90418 )

abnormal PR interval ( J:90418 )

prolonged P wave ( J:90418 )

abnormal QRS complex ( J:90418 )

muscle

muscle phenotype ( J:90418 )

N

dilated cardiomyopathy ( J:90418 )

muscle degeneration ( J:90418 )

respiratory system

pulmonary edema ( J:90418 )

decreased pulmonary respiratory rate ( J:90418 )

nervous system

nervous system phenotype ( J:90418 )

N

homeostasis/metabolism

pulmonary edema ( J:90418 )