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Phenotypes Associated with This Genotype
Genotype
MGI:3784844
Allelic
Composition
F2rl1tm1Cgh/F2rl1tm1Cgh
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
F2rl1tm1Cgh mutation (3 available); any F2rl1 mutation (60 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• mice exhibit faster recovery of the epidermal barrier compared to wild-type mice after acute barrier abrogation by tape stripping (J:111734)
• unlike in wild-type mice, lamellar body secretion is enhanced prior to and following barrier abrogation (J:111734)
• mice fail to exhibit apoptosis in stratum granulosum cells following tape stripping (J:130935)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory