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Phenotypes Associated with This Genotype
Genotype
MGI:3784684
Allelic
Composition
Tg(PDGFB-APPSwInd)J9Lms/0
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• at 5 to 7 months, mice exhibit amloid beta plaques
• between 16 and 21 months, all mice develop amyloid beta plaques
• neurodegeneration is indicated by an age dependent decrease in density of synaptophysin-immunoreactive presynaptic terminals

homeostasis/metabolism
• at 5 to 7 months, mice exhibit amloid beta plaques
• between 16 and 21 months, all mice develop amyloid beta plaques

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Alzheimer's disease DOID:10652 OMIM:104300
OMIM:502500
OMIM:604154
OMIM:608907
J:62290


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory