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Phenotypes Associated with This Genotype
Genotype
MGI:3784584
Allelic
Composition		 Msh2tm1Tts/Msh2tm1Tts
Nudt1tm1Tts/Nudt1tm1Tts
Genetic
Background		 involves: 129S/SvEv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msh2tm1Tts mutation (0 available); any Msh2 mutation (95 available)
Nudt1tm1Tts mutation (0 available); any Nudt1 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell physiology ( J:79732 )
• spleen cells show a significant increase in frameshift mutations at mononucleotide runs relative to wild-type when assayed with a reporter system

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory