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Phenotypes Associated with This Genotype
Genotype
MGI:3784013
Allelic
Composition		 Erc2tm1.1Sud/Erc2tm1.1Sud
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Erc2tm1.1Sud mutation (1 available); any Erc2 mutation (112 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal CNS synaptic transmission ( J:133656 )
• evoked IPSCs are moderately increased compared to wild-type
abnormal inhibitory postsynaptic currents ( J:133656 )
• evoked IPSCs are moderately increased compared to wild-type
abnormal synaptic neurotransmitter level ( J:133656 )
• readily releasable pool is moderately increased compared to wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory