Phenotypes Associated with This Genotype

Genotype
MGI:3783847

• Allelic Composition: Tg(Cryaa-AKR1B1)222Smch/0
• Genetic Background: involves: C57BL * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:106642 )

N • mice induced to become diabetic with streptozotocin injection do not develop cataracts

cataract ( J:106642 )

• 3-week old mice fed a 50% galactose diet, cataracts develop in transgenic animals, but not in non-transgenic mice; stages of cataract development reached correlates with level of transgene expression

homeostasis/metabolism

abnormal homeostasis ( J:106642 )