Phenotypes Associated with This Genotype

Genotype
MGI:3783547

• Allelic Composition: Bhlhe40^tm1.1Rhli/Bhlhe40^tm1.1Rhli
• Genetic Background: involves: 129S1/Sv * C57BL/6 * CD-1 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased susceptibility to pharmacologically induced seizures ( J:131834 )

• increased susceptibility to kainate-induced seizures

• homozygous mutant mice are viable and fertile with no apparent abnormality

• no obvious signs of autoimmune disease in mice one year of age

nervous system

increased susceptibility to pharmacologically induced seizures ( J:131834 )

• increased susceptibility to kainate-induced seizures

• homozygous mutant mice are viable and fertile with no apparent abnormality

• no obvious signs of autoimmune disease in mice one year of age