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Phenotypes Associated with This Genotype
Genotype
MGI:3777284
Allelic
Composition		 Fgrtm1Hev/Fgrtm1Hev
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgrtm1Hev mutation (0 available); any Fgr mutation (132 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal interferon-gamma secretion ( J:131738 )
• stimulated natural killer (NK) cells produce more NKR-P1C-induced IFN-gamma than wild-type NK cells
• however, INF-gamma production by NK T cells is normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory