Phenotypes Associated with This Genotype

Genotype
MGI:3777091

• Allelic Composition: Tg(Myh6-Mef2d)2Eno/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

liver vascular congestion ( J:130825 )

• liver is severely congested at 8 weeks of age

pulmonary vascular congestion ( J:130825 )

• lungs are severely congested at 8 weeks of age

increased heart atrium size ( J:130825 )

• mice display atrial enlargement at 8 weeks of age

cardiac fibrosis ( J:130825 )

• transgenic animals show extensive fibrosis at 8 weeks of age

cardiomyopathy ( J:130825 )

• hearts display hallmarks of remodeling and cardiomyopathy

muscle

cardiomyopathy ( J:130825 )

• hearts display hallmarks of remodeling and cardiomyopathy

homeostasis/metabolism

abnormal thrombosis ( J:130825 )

• animals show thrombosis at 8 weeks of age

liver/biliary system

liver vascular congestion ( J:130825 )

• liver is severely congested at 8 weeks of age

respiratory system

pulmonary vascular congestion ( J:130825 )

• lungs are severely congested at 8 weeks of age