Phenotypes for Tcf3 MGI:3776846 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Tcf3^tm1Wein/Tcf3^tm3Zhu
Genetic Background	involves: 129/Sv * 129S4/SvJaeSor * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf3^tm1Wein mutation (0 available); any Tcf3 mutation (39 available)
Tcf3^tm3Zhu mutation (0 available); any Tcf3 mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:47671 )

• postnatal survival is lower than normal but improved compared to Tcfe2a null mice

hematopoietic system

decreased pro-B cell number ( J:47671 )

immune system

decreased pro-B cell number ( J:47671 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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