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Phenotypes Associated with This Genotype
Genotype
MGI:3776488
Allelic
Composition		 Ahrtm1(AHR)Mym/Ahrtm1(AHR)Mym
Genetic
Background		 B6.129P2-Ahrtm1(AHR)Mym
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ahrtm1(AHR)Mym mutation (2 available); any Ahr mutation (109 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased physiological sensitivity to xenobiotic ( J:132380 )
• mice are resistant to the teratogenic effects of TCDD with no mice exhibiting altered palate development
• mice from mothers treated with TCDD exhibit a similar incidence of hydronephrosis as Ahrb-1 homozygotes but at a reduced severity

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory