About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3776434
Allelic
Composition		 Dll1tm1Gos/Dll1+
Jag2tm1Grid/Jag2tm1Grid
Genetic
Background		 involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dll1tm1Gos mutation (2 available); any Dll1 mutation (45 available)
Jag2tm1Grid mutation (1 available); any Jag2 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal organ of Corti morphology ( J:132241 )
• cells within the organ of Corti, including pillar cells, Dieter's cells and Hensen's cells, continue to proliferate between E14.5 and E17.5 unlike in wild-type mice
increased cochlear inner hair cell number ( J:132241 )
• cochlea exhibit a greater increase in inner hair cells than in Jag2tm1Grid homozygotes

nervous system
increased cochlear inner hair cell number ( J:132241 )
• cochlea exhibit a greater increase in inner hair cells than in Jag2tm1Grid homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory