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Phenotypes Associated with This Genotype
Genotype
MGI:3776094
Allelic
Composition
Agrptm2(HBEGF)Rpa/Agrptm2(HBEGF)Rpa
Genetic
Background
involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agrptm2(HBEGF)Rpa mutation (1 available); any Agrp mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• following treatment with diptheria toxin (DT) to specifically ablate NPY-expressing cells, mice fail to increase their food intake at a 10% loss of body weight and their intake dramatically decreased as their weight loss approaches 20%


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory