Phenotypes Associated with This Genotype

Genotype
MGI:3776081

• Allelic Composition: Agrp^{tm2(HBEGF)Rpa}/Agrp⁺
• Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal eating behavior ( J:132360 )

• adults injected with diptheria toxin (DT) to specifically ablate NPY-expressing cells cease to eat unlike similarly treated wild-type mice

• however, food consumption of neonates following injection with diptheria toxin to specifically ablate NPY-expressing cells is normal

growth/size/body

decreased body weight ( J:132360 )

• neonates injection with diptheria toxin (DT) to specifically ablate NPY-expressing cells exhibit an 11% decreased in body weight at weaning compared to similarly treated wild-type mice