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Phenotypes Associated with This Genotype
Genotype
MGI:3776027
Allelic
Composition		 Nrastm1Tyj/Nras+
Tg(Vil1-cre)20Syr/0
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrastm1Tyj mutation (1 available); any Nras mutation (44 available)
Tg(Vil1-cre)20Syr mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased physiological sensitivity to xenobiotic ( J:132357 )
• one week after exposure to 2.5% dextran sodium sulfate (DSS), colonic epithelium shows high resistance to the effects relative to wild-type and Kras mutant animals; sensitivity to DSS-induced apoptosis is strongly reduced

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory