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Phenotypes Associated with This Genotype
Genotype
MGI:3775763
Allelic
Composition
Ifnlr1tm1Palu/Ifnlr1tm1Palu
Genetic
Background
B6.Cg-Ifnlr1tm1Palu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ifnlr1tm1Palu mutation (0 available); any Ifnlr1 mutation (36 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• in the murine model for genital herpes, in which local administration of TLR3 and TLR9 ligands induces a strong antiviral response, viral titers were significantly higher in mutant mice and developed signs of disease to a higher extent than did the wild-type
• mutant mice were otherwise indistinguishable from wild-type mice with respect to clearance of a panel of different viruses


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory