Analysis Tools
reproductive system
azoospermia
(
J:118270
)
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• no live sperm are found in epididymis
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• testes show a 2.8-fold decrease in diploid cells and 4-fold increase in tetraploid cells relative to wild-type
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• no lumen is observed
• Seroli cell nuclei show disorganization and dislocalization
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• tubules show reduced diameters
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small testis
(
J:118270
)
|
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• testes are normally descended but only attain 31.1% of that in wild-type males
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• no mature or elongated spermatid or spermatozoa are found
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• germ cell development stops at stage around secondary spermatocyte to round spermatid
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• in three successive 2-week pairings with wild-type females, 14-week old males fail to impregnate the females; vaginal plugs were detected in females after mating
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endocrine/exocrine glands
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• no lumen is observed
• Seroli cell nuclei show disorganization and dislocalization
|
|
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• tubules show reduced diameters
|
small testis
(
J:118270
)
|
|
• testes are normally descended but only attain 31.1% of that in wild-type males
|
homeostasis/metabolism
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• significantly decreased relative to wild-type males
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cellular
azoospermia
(
J:118270
)
|
|
• no live sperm are found in epididymis
|
|
|
• testes show a 2.8-fold decrease in diploid cells and 4-fold increase in tetraploid cells relative to wild-type
|
|
|
• germ cell development stops at stage around secondary spermatocyte to round spermatid
|
