Phenotypes Associated with This Genotype

Genotype
MGI:3773758

• Allelic Composition: Id2^tm1Yyk/Id2^tm1Yyk; Tg(Wnt1)1Hev/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal branching of the mammary ductal tree ( J:96305 )

♀ • mammary glands of virgin females have excessive ductal side branching resembling that of pregnant wild-type mice

increased mammary gland tumor incidence ( J:96305 )

• develop mammary tumors at a similar rate to that seen in single hemizygous Tg(Wnt1)1Hev mice

mammary gland hyperplasia ( J:96305 )

♀ • mammary glands of virgin females have extensive, dense hyperplasia

neoplasm

increased mammary gland tumor incidence ( J:96305 )

• develop mammary tumors at a similar rate to that seen in single hemizygous Tg(Wnt1)1Hev mice

integument

abnormal branching of the mammary ductal tree ( J:96305 )

♀ • mammary glands of virgin females have excessive ductal side branching resembling that of pregnant wild-type mice

increased mammary gland tumor incidence ( J:96305 )

• develop mammary tumors at a similar rate to that seen in single hemizygous Tg(Wnt1)1Hev mice

mammary gland hyperplasia ( J:96305 )

♀ • mammary glands of virgin females have extensive, dense hyperplasia