Phenotypes Associated with This Genotype

Genotype
MGI:3773694

• Allelic Composition: Npr3^lgj-3J/Npr3^lgj-3J
• Genetic Background: C57BL/6J-Npr3^lgj-3J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:131428 )

• digits are often banded, twisted and deformed

clinodactyly ( J:131428 )

kinked tail ( J:131428 )

skeleton

abnormal axial skeleton morphology ( J:131428 )

• abnormal skeletal development results in an elongated body

abnormal vertebral column morphology ( J:131428 )

kyphosis ( J:131428 )

• severe thoracic kyphosis in older homozygotes

abnormal skeleton development ( J:131428 )

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:131428 )

• ABR testing shows elevated thresholds at all frequencies by 3 to 5 months of age