Phenotypes Associated with This Genotype

Genotype
MGI:3773316

• Allelic Composition: Mif^tm1Dvd/Mif^tm1Dvd
• Genetic Background: B6.129S4-Mif^tm1Dvd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

BBN-induced bladder cancer is less aggressive in Mif^tm1Dvd/Mif^tm1Dvd mice than in wild type and does not invade muscle layers

neoplasm

decreased incidence of tumors by chemical induction ( J:126543 )

• mice treated with N-butyl-N-(-4-hydroxybutyl)-nitrosamine (BBN) develop less aggressive bladder cancer than wild-type mice, with no invasion into muscle layers as seen in wild-type

homeostasis/metabolism

decreased incidence of tumors by chemical induction ( J:126543 )

• mice treated with N-butyl-N-(-4-hydroxybutyl)-nitrosamine (BBN) develop less aggressive bladder cancer than wild-type mice, with no invasion into muscle layers as seen in wild-type