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Phenotypes Associated with This Genotype
Genotype
MGI:3773306
Allelic
Composition
Tg(Scg2-tTA)1Jt/0
Tg(tetO-Clock)1Jt/0
Genetic
Background
involves: C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Scg2-tTA)1Jt mutation (1 available)
Tg(tetO-Clock)1Jt mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• double transgenic mice display a circadian period that is shortened by 1 hour relative to wild-type mice
• treatment with doxycycline to suppress transgenic Clock expression demonstrates a rapid switch-off of expression and rapid turn-on upon return to normal water


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory