Phenotypes Associated with This Genotype

Genotype
MGI:3773148

• Allelic Composition: Atrn^mg-3J/Atrn^mg-3J; Tg(ACTB-Atrnl1)B4Tmg/0
• Genetic Background: involves: C3HeB/FeJ * C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

brain vacuoles ( J:130463 )

• brain vacuolation is rescued with only sparse, scattered vacuoles observed at 3 months

• mild to moderate vacuolation occurs at 6 months

• Background Sensitivity: rescue of vacuolation occurs on both a C3H/HeJ and C57BL/6J background

pigmentation

darkened coat color ( J:130463 )

• mice exhibit a partially rescued coat color that is described as dark agouti

integument

darkened coat color ( J:130463 )

• mice exhibit a partially rescued coat color that is described as dark agouti