Analysis Tools
growth/size/body
weight loss
(
J:108700
)
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• mice whom paternally inherit the knockout allele display 10-20% decline in weight as they age
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cellular
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• paternal transmission of the deletion leads to the biallelic expression of several genes that are normally only expressed on the maternal allele
• the genes examined that lose imprinting are Axcl2, Kcnq1, Cdkn1c, Slc22a18, Phlda2, Osbpl5
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