Phenotypes for Ascl2 Kcnq1ot1 MGI:3772941 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ascl2^tm1Alj/Ascl2⁺ Kcnq1ot1^tm1.1Mjh/Kcnq1ot1⁺
Genetic Background	involves: 129 * C57BL/6 * ICR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ascl2^tm1Alj mutation (0 available); any Ascl2 mutation (13 available)
Kcnq1ot1^tm1.1Mjh mutation (0 available); any Kcnq1ot1 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

embryo phenotype ( J:130399 )

N	• no embryonic lethality is observed in mice maternally inheriting the Ascl2^tm1Alj allele

cellular

abnormal imprinting ( J:130399 )

• embryonic lethality associated with maternal transmission of Ascl2^tm1Alj allele is prevented by the addition of the Kcnq1^tm1.1Mjh allele due to a lack of paternal imprinting of genes in the distal portion of chromosome 7

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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