Phenotypes Associated with This Genotype

Genotype
MGI:3771172

• Allelic Composition: Gpihbp1^tm1Sgy/Gpihbp1^tm1Sgy
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating HDL cholesterol level ( J:129764 )

increased circulating cholesterol level ( J:129764 )

increased circulating VLDL cholesterol level ( J:129764 )

increased circulating triglyceride level ( J:129764 )

• prior to weaning. mice exhibit slightly increased triglyceride levels (120+/-12 compared to 23+/-16 mg/dl in wild-type mice)

• by 7 to 10 weeks of age, mice exhibit triglyceride levels over 1000 mg/dl and as high as 5000 mg/dl in some mice