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Phenotypes Associated with This Genotype
Genotype
MGI:3770148
Allelic
Composition
Bdnftm1Limm/Bdnftm1Limm
Tg(Camk2a-cre)T50Stl/0
Genetic
Background
involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bdnftm1Limm mutation (0 available); any Bdnf mutation (41 available)
Tg(Camk2a-cre)T50Stl mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• female, but not male, mice exhibit reduced preference for a natural reward in sucrose preference tests compared to wild-type mice
• female, but not male, mice exhibit more immobility when placed in swim test than wild-type mice
• unlike wild-type mice, female and male mice do not exhibit any decrease in immobility following administration of desipramine
• male, but not female, mice exhibit increased locomotor activity compared to same sex wild-type mice
• however, activity levels are normal after 4 days of habituation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory