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Phenotypes Associated with This Genotype
Genotype
MGI:3769382
Allelic
Composition		 Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Kat8tm1Thl/Kat8tm1Thl
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(cre/ERT2)Thl mutation (0 available); any Gt(ROSA)26Sor mutation (944 available)
Kat8tm1Thl mutation (0 available); any Kat8 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased fibroblast proliferation ( J:128936 )
• following treatment with tamoxifen, mouse embryonic fibroblasts exhibit a decrease in proliferation compared to wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory