About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3769348
Allelic
Composition		 Jak3tm1Ljb/Jak3tm1Ljb
Rag1tm1Mom/Rag1tm1Mom
Genetic
Background		 involves: 129S4/SvJae * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak3tm1Ljb mutation (1 available); any Jak3 mutation (84 available)
Rag1tm1Mom mutation (49 available); any Rag1 mutation (120 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:56629 )
N
• unlike Jak3 null mice that are wild-type for Rag1, no splenomegaly is seen
abnormal splenic cell ratio ( J:56629 )
• FACs profile of spleens resemble those of mice homozygous null for Rag1 alone

hematopoietic system
abnormal splenic cell ratio ( J:56629 )
• FACs profile of spleens resemble those of mice homozygous null for Rag1 alone

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory