Phenotypes Associated with This Genotype

Genotype
MGI:3768765

• Allelic Composition: Herc4^{Gt(RRH224)Byg}/Herc4^{Gt(RRH224)Byg}
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

kinked sperm flagellum ( J:128937 )

♂ • mice exhibit a 3-fold higher number of sperm with marked angulation of the tails

asthenozoospermia ( J:128937 )

♂ • spermatozoon forward motility is half that of wild-type counterparts

arrest of spermatogenesis ( J:128937 )

♂ • cytoplasmic droplets are associated with angulations of the sperm tails, suggesting final maturation of the spermatozoa fails

reduced male fertility ( J:128937 )

♂ • male mice sire litters that are half that in number compared to litters produced by wild-type males

cellular

kinked sperm flagellum ( J:128937 )

♂ • mice exhibit a 3-fold higher number of sperm with marked angulation of the tails

asthenozoospermia ( J:128937 )

♂ • spermatozoon forward motility is half that of wild-type counterparts