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Phenotypes Associated with This Genotype
Genotype
MGI:3768657
Allelic
Composition		 Tg(PDGFB-GPR37)20Ryot/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:140326 )
N
• unlike other transgene lines over-expressing GPR37, mice do not exhibit dopaminergic neuron loss

behavior/neurological

homeostasis/metabolism
increased dopamine level ( J:128745 )
• DOPAC and vesicular dopamine levels are increased in the striatum compared to in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory