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Phenotypes Associated with This Genotype
Genotype
MGI:3768529
Allelic
Composition		 Jam3tm1Rha/Jam3tm1Rha
Tg(Tek-Jam3)1Maal/?
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jam3tm1Rha mutation (0 available); any Jam3 mutation (24 available)
Tg(Tek-Jam3)1Maal mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:121841 )
N
• unlike Jam3tm1Rha homozygotes, mice do not exhibit any postnatal lethality due to housing conditions

reproductive system

digestive/alimentary system

immune system
immune system phenotype ( J:121841 )
N
• unlike Jam3tm1Rha homozygotes, leukocyte homeostasis is normal

growth/size/body
enlarged esophagus ( J:121841 )

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory