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Phenotypes Associated with This Genotype
Genotype
MGI:3768522
Allelic
Composition		 Twist1tm1Bhr/Twist1tm1Bhr
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Twist1tm1Bhr mutation (4 available); any Twist1 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
internal hemorrhage ( J:128714 )
• at E11.5, blood pooling in the cranial region is observed

limbs/digits/tail
abnormal forelimb morphology ( J:128714 )
• at E11.5, forelimbs are reduced in size compared to wild-type mice

nervous system

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory