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Phenotypes Associated with This Genotype
Genotype
MGI:3768260
Allelic
Composition
Hephsla/Hephsla
Genetic
Background
B6.Cg-Hephsla
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hephsla mutation (1 available); any Heph mutation (11 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system

homeostasis/metabolism
• total body iron is decreased

embryo
• defect in placental iron transport; when iron is administered continuously in food of pregnant females, a significant reduction in iron transfer to mutant fetuses is observed


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory