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Phenotypes Associated with This Genotype
Genotype
MGI:3768129
Allelic
Composition
Tg(THY1-SNCA*A30P)TS2Sud/0
Genetic
Background
involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(THY1-SNCA*A30P)TS2Sud mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mice show onset of motoneuron disease at ~9-10 months
• insoluble alpha-synuclein aggregates form in asymptomatic and symptomatic transgenic mice in terms of neuropathology


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory