Phenotypes Associated with This Genotype

Genotype
MGI:3767472

• Allelic Composition: Pax6^Sey/Pax6^Sey-H
• Genetic Background: involves: 101/H * C3H/HeH * C57BL/10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal maxillary shelf morphology ( J:8534 )

• at E13.5, the maxillae are not fused and there is only a small bilobed protrusion in the frontonasal position that in some mice may fuse on one side

abnormal face development ( J:8534 )

• facial development is retarded compared to wild-type and Pax6^Sey homozygotes

absent snout ( J:8534 )

vision/eye

anophthalmia ( J:8534 )

• while small bleds are present in the area occupied by the eye they contain no brain involvement

embryo

decreased embryo size ( J:8534 )

• at E13.5, mice are smaller than wild-type and Pax6^sey homozygotes

skeleton

abnormal maxillary shelf morphology ( J:8534 )

• at E13.5, the maxillae are not fused and there is only a small bilobed protrusion in the frontonasal position that in some mice may fuse on one side

digestive/alimentary system

abnormal maxillary shelf morphology ( J:8534 )

• at E13.5, the maxillae are not fused and there is only a small bilobed protrusion in the frontonasal position that in some mice may fuse on one side

growth/size/body

abnormal maxillary shelf morphology ( J:8534 )

• at E13.5, the maxillae are not fused and there is only a small bilobed protrusion in the frontonasal position that in some mice may fuse on one side

abnormal face development ( J:8534 )

• facial development is retarded compared to wild-type and Pax6^Sey homozygotes

absent snout ( J:8534 )

decreased embryo size ( J:8534 )

• at E13.5, mice are smaller than wild-type and Pax6^sey homozygotes