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Phenotypes Associated with This Genotype
Genotype
MGI:3767253
Allelic
Composition		 Nfiatm1Rmg/Nfiatm1Rmg
Tg(Hoxb7-EGFP)33Cos/?
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfiatm1Rmg mutation (1 available); any Nfia mutation (28 available)
Tg(Hoxb7-EGFP)33Cos mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Nfiatm1Rmg/Nfia+ Tg(Hoxb7-EGFP)33Cos and Nfiatm1Rmg/Nfiatm1Rmg Tg(Hoxb7-EGFP)33Cos mice have ureteral defects

renal/urinary system
abnormal kidney morphology ( J:122749 )
• dysplastic kidney
abnormal ureter development ( J:122749 )
• 33% of mutants exhibit ureteral development abnormalities, that include proximal flexion of the ureter and ureter dilation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory