hematopoietic system
|
• reduction in hematopoietic tissue in both the liver and bone marrow
|
|
• anemia is most severe at a young age and tends to diminish with increasing age
• iron-dextran injection resolves the anemia
|
|
• red blood cell count is reduced to about 3/4 of the normal value
(J:64261)
(J:128474)
|
|
• slight reduction
|
|
• slight reduction in mean cell volume
|
|
• erythrocytes show great variation in size and form
|
macrocytosis
(
J:128474
)
|
• some cells are macrocytic
|
microcytosis
(
J:128474
)
|
• many microcytic cells
|
|
• macrocytic cells with marked polychromasia
|