Phenotypes Associated with This Genotype

Genotype
MGI:3767003

• Allelic Composition: hlb243/hlb243
• Genetic Background: C57BL/6J-hlb243/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating cholesterol level ( J:82961 )

• at 13 weeks of age, after consuming an atherogenic diet for >5 weeks, a homozygous mutant mouse had a 4-hour fasted plasma total cholesterol level of 517 mg/dl

increased circulating HDL cholesterol level ( J:82961 )

• at 13 weeks of age, after consuming an atherogenic diet for >5 weeks, a homozygous mutant mouse had a 4-hour fasted plasma HDL cholesterol level of 129 mg/dl