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Phenotypes Associated with This Genotype
Genotype
MGI:3766325
Allelic
Composition
Eno2tm1(DTA)Hsak/?
Tg(Or10j5-cre,-ECFP)17Hsak/?
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eno2tm1(DTA)Hsak mutation (1 available); any Eno2 mutation (55 available)
Tg(Or10j5-cre,-ECFP)17Hsak mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
• olfactory sensory neurons are absent in the ventral zone and in some of the dorsal zone of the olfactory bulb epithelium
• no expression of class II olfactory receptor genes in the dorsal or ventral zones of the olfactory epithelium

behavior/neurological
• mice fail to show innate avoidance behavior to trimethyl-thiazoline scent (found in fox urine)

nervous system
• olfactory sensory neurons are absent in the ventral zone and in some of the dorsal zone of the olfactory bulb epithelium
• no expression of class II olfactory receptor genes in the dorsal or ventral zones of the olfactory epithelium

craniofacial
• olfactory sensory neurons are absent in the ventral zone and in some of the dorsal zone of the olfactory bulb epithelium
• no expression of class II olfactory receptor genes in the dorsal or ventral zones of the olfactory epithelium

respiratory system
• olfactory sensory neurons are absent in the ventral zone and in some of the dorsal zone of the olfactory bulb epithelium
• no expression of class II olfactory receptor genes in the dorsal or ventral zones of the olfactory epithelium

growth/size/body
• olfactory sensory neurons are absent in the ventral zone and in some of the dorsal zone of the olfactory bulb epithelium
• no expression of class II olfactory receptor genes in the dorsal or ventral zones of the olfactory epithelium


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory