Phenotypes Associated with This Genotype

Genotype
MGI:3766087

• Allelic Composition: Rarb^tm1Mma/Rarb^tm1Mma; Rarg^tm1Ipc/Rarg⁺
• Genetic Background: involves: 129S2/SvPas * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

persistent hyperplastic primary vitreous ( J:43344 )

• 5 of 6 E18.5 mutants show a bilateral persistent hyperplastic primary vitreous

skeleton

abnormal skeleton morphology ( J:43344 )

• 46% of mutants exhibit skeletal malformations

abnormal basioccipital bone morphology ( J:43344 )

• 1 of 13 (8%) mutants exhibit a posterior tubercle on the basioccipital bone

abnormal sternum morphology ( J:43344 )

• 1 of 13 (8%) exhibit sternum malformations

fusion of atlas and odontoid process ( J:43344 )

• 3 of 13 (23%) of mutants exhibit fusion of C1-AA with C2 dens

split cervical axis ( J:43344 )

• 2 of 13 (15%) mutants exhibit a bifid C2

craniofacial

abnormal basioccipital bone morphology ( J:43344 )

• 1 of 13 (8%) mutants exhibit a posterior tubercle on the basioccipital bone