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Phenotypes Associated with This Genotype
Genotype
MGI:3766086
Allelic
Composition		 Rarbtm1Mma/Rarb+
Rargtm1Ipc/Rarg+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rarbtm1Mma mutation (0 available); any Rarb mutation (40 available)
Rargtm1Ipc mutation (2 available); any Rarg mutation (150 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
absent metoptic pillar ( J:43344 )
• 4 of 12 mutants exhibit agenesis of the metoptic pillar

vision/eye
absent metoptic pillar ( J:43344 )
• 4 of 12 mutants exhibit agenesis of the metoptic pillar
persistent hyperplastic primary vitreous ( J:43344 )
• 5 of 6 E18.5 mutants show a bilateral persistent hyperplastic primary vitreous

skeleton
absent metoptic pillar ( J:43344 )
• 4 of 12 mutants exhibit agenesis of the metoptic pillar

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory