Phenotypes Associated with This Genotype

Genotype
MGI:3766055

• Allelic Composition: Cdkn2a^tm1.1Brn/Cdkn2a^tm1.1Brn
• Genetic Background: involves: 129P2/OlaHsd * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

neoplasm ( J:71393 )

N • mice display no increased predisposition to developing tumors and do not exhibit any defects in cell cycle regulation

decreased incidence of tumors by chemical induction ( J:125189 )

• DMBA-induced tumors occur later and exhibit a much narrower diversity than those that develop in DMBA treated Cdkn2a^tm1.1Brn Cdkn2b^tm1Brn homozygotes

homeostasis/metabolism

decreased incidence of tumors by chemical induction ( J:125189 )

• DMBA-induced tumors occur later and exhibit a much narrower diversity than those that develop in DMBA treated Cdkn2a^tm1.1Brn Cdkn2b^tm1Brn homozygotes