Mouse Genome Informatics
hm
    Adamts13tm1Myta/Adamts13tm1Myta
involves: 129S6/SvEvTac
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
hematopoietic system
• there are about 2-fold more platelet counts in the serum 15 minutes after challenge with collagen and epinephrine

homeostasis/metabolism
• 29% increase in von Willebrand factor antigen in blood
• 46% increase in FVIII activity in the blood
• there are about 2-fold more platelet counts in the serum 15 minutes after challenge with collagen and epinephrine
• thrombus volume is increased when blood is perfused for 5 minutes over a collagen coated surface

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Thrombotic Thrombocytopenic Purpura, Congenital; TTP 274150 J:125786