Phenotypes Associated with This Genotype

Genotype
MGI:3761934

• Allelic Composition: Kcnj8^gnite/Kcnj8^gnite
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to Herpesvirales infection induced morbidity/mortality ( J:105543 , J:126658 )

• mice are extremely sensitive to infection by mouse cytomegalovirus (MCMV) (J:105543)

• these mice die 2-3 days following MCMV infection (J:105543)

• mice die between 36 hours and 3 days after infection with mouse cytomegalovirus without high titers of virus or evidence of antecedent sickness (J:126658)

immune system

increased susceptibility to Herpesvirales infection induced morbidity/mortality ( J:105543 , J:126658 )

• mice are extremely sensitive to infection by mouse cytomegalovirus (MCMV) (J:105543)

• these mice die 2-3 days following MCMV infection (J:105543)

• mice die between 36 hours and 3 days after infection with mouse cytomegalovirus without high titers of virus or evidence of antecedent sickness (J:126658)