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Phenotypes Associated with This Genotype
Genotype
MGI:3761928
Allelic
Composition		 Ptentm1Mro/Ptentm1Mro
Tg(KLK3-cre)D4Trp/0
Genetic
Background		 involves: 129P2/OlaHsd * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1Mro mutation (1 available); any Pten mutation (81 available)
Tg(KLK3-cre)D4Trp mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
prostate gland epithelial hyperplasia ( J:99524 )
• mutants show a 2-fold higher number of proliferating (BrdU-positive) cells at 4-5, 7-9, and 10-14 months

endocrine/exocrine glands
prostate gland epithelial hyperplasia ( J:99524 )
• mutants show a 2-fold higher number of proliferating (BrdU-positive) cells at 4-5, 7-9, and 10-14 months

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory